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Weight gain was associated with pathologic cardiac remodeling and an increased long-term risk for HF, according to new data from the Dallas Heart Study published in the Journal of the American Heart Association. “Any weight gain may lead to abnormal changes in the heart above and beyond one's baseline weight,” Ian J. Neeland, MD, a cardiologist, assistant professor of medicine and Dedman Family Scholar in Clinical Care at University of Texas Southwestern Medical Center in Dallas and Cardiology Today Next Gen Innovator, said in an interview. “This means that prevention of HF should focus on weight loss or, if meaningful weight loss cannot be achieved, the focus should be on maintaining one's weight and preventing weight gain. Counseling to maintain weight stability may be an important preventive strategy among high-risk individuals.”
Biotronik announced FDA approval of two implantable cardioverter defibrillator systems for the improvement of care for patients with HF, according to a press release. The Intica DX and Intica cardiac resynchronization therapy (CRT)-DX ICD systems are cardiac rhythm management devices that eliminate the need for an atrial lead while providing physicians with critical diagnostic information based on a true atrial signal, according to the release.
In mostly healthy younger adults, the Healthy Heart Score predicted premature atherosclerotic CVD events moderately well, making it a viable tool for risk assessment and counseling for primary prevention of the disease, according to findings published in JAMA Internal Medicine. “Mortality rates associated with atherosclerotic cardiovascular disease (ASCVD) have steadily declined in past decades owing to advances in prevention, detection, and treatment,” Holly C. Gooding, MD, MS, from Boston Children’s Hospital, and colleagues wrote. “Unfortunately, scientists caution this trend may soon reverse owing to increasing obesity rates and unhealthy diet and exercise patterns in younger individuals. Adolescents and young adults are a prime target for ASCVD prevention efforts, especially because most do not yet have major clinical risk factors for ASCVD, such as hypertension, hyperlipidemia and diabetes.”
Patients with chronic deep vein thrombosis and postthrombotic syndrome can be treated safely and effectively with catheter-assisted thrombolysis therapy, according to the results of the ACCESS PTS study, presented at the Society for Vascular Medicine Scientific Sessions in New Orleans.“Using minimally invasive endovascular techniques, we have been able to show that successful recanalization of chronic deep vein thrombosis (DVT) can occur and can significantly improve quality of life while decreasing postthrombotic venous scores,” study presenter Mark J. Garcia, MD, FSIR, FACR, president and medical director of Vascular & Interventional Associates of Delaware and EndoVascular Consultants, said in an interview with Cardiology Today’s Intervention.
Despite consistent counseling, the use of prescription smoking cessation medications was low in older patients after an MI, according to a research letter published in JAMA Cardiology. Neha J. Pagidipati, MD, MPH, of Duke Clinical Research Institute at Duke University in Durham, North Carolina, and colleagues reviewed data from 9,193 patients aged at least 65 years who had an MI and were current or recent smokers.
PHILADELPHIA — Acute kidney injury is common, and community-acquired and hospital-acquired acute kidney injury lead to similar mortality rates, according to a speaker here. “Acute kidney injury is not just an in-hospital syndrome, and it is suggested that it can occur from infections from primary care, outpatient procedures and inpatient procedures,” Peter A. McCullough, MD, MPH, of Baylor University Medical Center, said. “Multiple studies have demonstrated that roughly one-third of acute kidney injury cases result in some underlying cause of worsening of kidney disease.”
To ensure the intended balance between encouraging innovation in drug development and accelerating the availability of lower cost alternatives to innovator drugs, the FDA held a forum to provide the public an opportunity to submit comments concerning administration of the Hatch-Waxman Amendments.“In too many places people cannot afford the medicines that they need,” Scott Gottlieb, MD, FDA Commissioner, said during his opening remarks. “We have a system that supports market-based pricing for innovation as a way to provide proper incentives to entrepreneurs for taking on the uncertainty of these costly and high-risk endeavors. But that means we also have to have a system that allows for vigorous competition once patent rights have lapsed on these conventions.”
Weight gain from early to middle adulthood was associated with increased risk for morbidity and mortality, and decreased the odds of healthy aging, according to new findings published in JAMA.“It is unclear how weight gain during the transition from early to middle adulthood, when most weight gain occurs, relates to subsequent health consequences. Recommendations for preventing weight gain during adulthood are lacking in public health guidelines,” Yan Zheng, MD, PhD, from the department of nutrition at Harvard T.H. Chan School of Public Health, and colleagues wrote. “Compared with studies of attained weight or BMI, an investigation of weight change may better capture the effect of excess fat because it factors in individual differences in frame size and lean mass that are difficult to measure in population studies.”
Researchers have developed a risk score using seven factors that can determine which patients after cryptogenic stroke or transient ischemic attack are at risk for atrial fibrillation, according to a recent study. Adults with TIA or cryptogenic stroke are at an increased risk for another stroke, and AF has been shown to be an independent risk factor for second stroke.
While a series of announcements by Senate Republicans seem to indicate that for the time being attempts both to replace and repeal the ACA have stalled, AMA president David O. Barbe, MD, warned the battle to protect health care for Americans continues. “The health reform debate is by no means over. Congress must begin a collaborative process that produces a bipartisan approach to improve health care in our country,” he said in a statement.
In patients with critical limb ischemia who have undergone endovascular or surgical revascularization, a frailty index was a risk factor for amputation-free survival at 2 years, according to new findings.Researchers conducted a retrospective study of 266 patients who underwent endovascular or surgical infrapopliteal revascularization of 325 limbs between 2007 and 2015.
In its response to the physician fee schedule proposed rule released by CMS, the AMA noted numerous positive changes that have the potential to improve patient care and save taxpayer dollars, including a request for information on regulatory relief, expansion of the Diabetes Prevention Program, consolidation and modernization of the legacy value-based payment systems and delayed implementation of appropriate use criteria.“The annual physician fee schedule update is a chance for CMS to modify Medicare policy to ensure the best possible treatment options for patients,” David O. Barbe, MD, president of AMA said in a press release. “The AMA is encouraged by many of the proposed changes and applauds the Administration for working with the AMA to address physician concerns. We will submit formal comments to CMS before the final rule is released later this year.”
The decrease in 30-day readmissions in Medicare fee-for-service beneficiaries with acute MI, HF and pneumonia was associated with a decrease in 30-day mortality rates after discharge, according to a study published in JAMA. Kumar Dharmarajan, MD, MBA, assistant professor of medicine at Yale School of Medicine and faculty at the Yale-New Haven Hospital Center for Outcomes Research and Evaluation, and colleagues analyzed data from patients aged at least 65 years who were hospitalized with acute MI, HF or pneumonia from 2008 to 2014. All-cause readmissions were included in this retrospective review.
New data have linked access-site and non-access-site bleeding after transcatheter aortic valve replacement to increased mortality, with risk being particularly high with non-access-site bleeding.“Although TAVR has been consistently associated with lower rates of bleeding events than conventional surgery, the differential prognostic impact of access-site and non-access-site bleeding in the setting of TAVR is unknown,” the researchers wrote.
PHILADELPHIA — There is a strong link between heart failure with preserved ejection fraction and diabetes, and the conditions often make each other worse, a speaker said at the Heart in Diabetes Medical Conference. Ejection fraction is an important measurement in the diagnosis and surveillance of heart failure (HF), however, it is possible for patients with normal ejection fraction to have HF, and this form of the disease, HF with preserved ejection fraction, or HFpEF, is becoming increasingly prevalent, Eldrin F. Lewis, MD, MPH, FAHA, cardiologist from Brigham and Women’s Hospital and associate professor of medicine at Harvard Medical School, said during a presentation.
Cardiovascular disease is an important risk factor for rapid progression of glaucoma disease, regardless of IOP, according to a study. Two cohorts of patients with glaucoma, respectively defined as rapid and non-rapid progressors based on the annual rate of visual field change (decline of mean deviation more or less than 1 dB/year), were retrospectively reviewed and compared to determine the demographic, intraocular and systemic risk factors potentially contributing to progression.
Patients with atrial fibrillation who received care from a cardiologist within 90 days after diagnosis had a decreased risk for stroke, according to a study published in the Journal of the American College of Cardiology.“The important message here is that getting early cardiology care was associated with early prescription of drugs specifically for preventing stroke,” Mintu Turakhia, MD, MAS, associate professor of cardiovascular medicine and director of research at the Center for Digital Health at Stanford University in California and director of cardiac electrophysiology at the VA Palo Alto Health Care System, said in a press release. “These findings show that it is important to think of these interventions at the time of diagnosis.”
PCI with complete revascularization yields similar outcomes to CABG, according to newly published data.“CABG offers a better survival rate compared with PCI in patients with severe [CAD], multivessel disease, and diabetes. Therefore, CABG has been considered the standard revascularization strategy in the treatment of severe [CAD],” the researchers wrote.
Participants who ate a healthier plant-based diet had a decreased risk for CHD, according to a study published in the Journal of the American College of Cardiology. “When we examined the associations of the three food categories with heart disease risk, we found that healthy plant foods were associated with lower risk, whereas less healthy plant foods and animal foods were associated with higher risk,” Ambika Satija, ScD, a postdoctoral fellow at the Harvard T.H. Chan School of Public Health, said in a press release. “It’s apparent that there is a wide variation in the nutritional quality of plant foods, making it crucial to take into consideration the quality of foods in a plant-based diet.”
The use of rivaroxaban or warfarin after endovascular or open peripheral artery procedures confers similar safety and efficacy outcomes, according to new findings.Researchers conducted a retrospective study of 94 patients who were prescribed rivaroxaban (Xarelto, Janssen Pharmaceuticals; n = 44; mean age, 61 years) or warfarin (n = 50; mean age, 64 years) for stroke prevention or venous thromboembolism treatment after a peripheral artery procedure at a single center between December 2012 and August 2014.